slang
The term "copium" is derived from the words "cope" (meaning to manage or confront a difficult situation in an effort to feel better) and "opium" (an addictive drug that can induce a sense of well-being). When someone accuses another person of using "copium," they are mocking them by suggesting that, rather than accepting they are wrong or admitting defeat, the person is clinging to something that helps them feel better or diverts attention from their loss.
Origin of meme image: “Copium” was popularized on 4chan in an image of Pepe the Frog. In 2019, a 4chan user posted an image of the character Pepe the Frog (a prolific meme character) hooked to a ventilator labeled “COPIUM.” The image soon became a popular reaction image on the site.